Description

Otonkoski et al described an autosomal-dominant syndrome of hypoglycemia after physical exercise associated with hyperinsulinemia (exercise-induced hyperinsulinism, or EIHI). Infusion of pyruvate in these patients can trigger release of insulin. The authors are from Haartman Institute at the University of Helsinki, University Children's Hospital in Dusseldorf and Karolinska Institute in Stockholm.

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